Imaris 11 – Automate the Routine, Amplify the Insight

Imaris 11 introduces Workflows, an intuitive step-by-step protocol system designed for researchers at every level.

Introducing Workflows – Step-by-Step 3D Image Analysis, Simplified

By automating repetitive image analysis tasks, Imaris helps you save time, ensure consistency, and focus on meaningful insights.

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Why Imaris? — From Bottleneck to Breakthrough

Image analysis is often repetitive and time-consuming, with challenges in sharing exact protocols and achieving reproducible results.

Imaris 11 Workflows address these issues by combining automation and batch processing to standardize analysis and enhance collaboration.

Workflows automatically record and store every analysis step, allowing researchers to efficiently process large datasets, reproduce results, and share methods seamlessly.

Create, Reuse, and Share Workflows Effortlessly

Protocol Creation Inside Imaris

Protocol Creation Inside Imaris: Build complete image analysis protocols directly within Imaris Surpass.

Batchable Workflows

Batchable Workflows: Automate entire workflows—including steps requiring manual input—for flexible, large-scale analysis.

Export and Import Workflows:

Export and Import Workflows: Share workflows between users or projects to promote collaboration and reproducibility.

Beginner-Friendly

Beginner-Friendly: Predefined workflows help new users get started with analysis quickly and easily.

Application

NeurosciencesMicroglial Synapse Engulfment 

Imaris 11 simplifies microglial synapse engulfment analysis, transforming a complex, time-intensive process into a streamlined workflow. Surface segmentation detects microglia, while automated algorithms quantify engulfed synapses.

Workflows dramatically reduce analysis time while ensuring reproducibility and allowing researchers to compare synaptic engulfment between experimental groups with batch protocols.


Vasculature ResearchHeart Vasculature Morphology

Analyzing heart vasculature is challenging: complex vessel networks require precise segmentation, manual tracing is time-consuming, and comparing cardiac compartments demands consistent methodology. 

Imaris 11 Workflows integrate machine learning Pixel Classification for automated vessel segmentation with Filament Tracer for precise quantification of vessel length and diameter, enabling reproducible analysis across multiple heart samples and compartments—transforming complex cardiac analysis into an efficient, shareable protocol.


Cells & TissuesSingle-Cell Analysis of TFEB activation 

Quantifying lysosomes and TFEB expression at the single-cell level traditionally requires multiple segmentation steps, making reproducibility challenging. 

Imaris 11 Workflows streamline this protocol by integrating Surface segmentation of cells and nuclei with Spot detection for lysosomes and TFEB into one automated, reproducible workflow. Statistics are compiled per cell while Batch Workflows enable consistent analysis and direct comparison across experimental groups through Vantage Plotting Tools.

11 Powerful Features to Accelerate Discovery

Discover eleven powerful new features that elevate your analysis experience, streamline workflows, and deliver a transformative leap in data analysis. These innovations cover every essential step, including image preprocessing, quantification, visualization, batch processing, comparisons, and data plotting.

  • Workflow basics - Execute, Export, Import
  • Batch Workflow with Manual Steps
  • Analyse in Surface Regions of Interests (ROIs)
  • Batch importing Surfaces and Spots into Cell
  • Batch Snapshots and navigate between Views
  • 1D & 2D Vantage for Comparative Analysis
  • Machine Learning Filtering of unwanted Spots
  • Extract Selected Statistics in one table
  • Batch Animations for Consistency
  • Mask or Delete Channels in a Batch mode
  • Two Options for Spine Diameter Calculations

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