OI Academy | Webinar
Combining Fluorescence Microscopy and 3D Reconstruction to Investigate Neuron-glia Interaction in Different Neurological Diseases
Dr. Danielle Beckman, Project Scientist at the California National Primate Research Center, will introduce how they apply high-resolution confocal microscopy to help the development of different primate models for neurological disorders. She will also show how acquisition of z-stack images in association with 3D reconstruction performed at Imaris helps them investigate neurodegeneration and neuroinflammation in different disease models.
Learning Objectives:
- Microglia morphology: Learn how to create and edit 3D surfaces to analyse microglia volume and interaction with other cell types. Understand what the indicators are for microglia activation and neuroinflammation.
- Viral infections: Discover how to identify and quantify different markers for viral infection.
- Neuronal death: Understand how to detect neurons dying using multilabel confocal microscopy, especially in combination with neuroinflammatory markers
